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Marcaillou-le Baut, Claire; Haure, Joel; Mondeguer, Florence; Courcoux, Anne; Dupuy, Beatrice; Penisson, Christian. |
The objective of this study was to identify a possible effect of food on the acceleration of decontamination in blue mussels, Mytilus edulis, containing diarrhetic toxins belonging to the okadaic acid (OA) structural group. An experimental protocol was designed to describe and compare the decontamination kinetics and detoxification rates of naturally OA-contaminated mussels that had either received or not received food for three weeks. The protocol was applied in two trials (in June 2006 and June 2007, called Ker06 and Ker07), conducted one year apart on samples of mussels collected in the same area, at the same season. Okadaic acid (OA), the main lipophilic toxin produced by the toxic alga Dinophysis acuminata, was analysed over the course of the... |
Tipo: Text |
Palavras-chave: Mussel; Feeding; Digestive gland; Depuration; Okadaic acid; Acyl esters; Marine lipophilic biotoxins; Mass spectrometry. |
Ano: 2010 |
URL: http://archimer.ifremer.fr/doc/00025/13650/10883.pdf |
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Fux, E; Marcaillou-le Baut, Claire; Mondeguer, Florence; Bire, R; Hess, Philipp. |
It has been demonstrated that polymeric resins can be used as receiving phase in passive samplers designed for the detection of lipophilic marine toxins at sea and was referred to as solid phase adsorption toxin tracking (SPATT). The present study describes the uptake and desorption behaviour of the lipophilic marine toxins okadaic acid (OA) and dinophysistoxin-1 (DTX1) from Prorocentrum lima cultures by five styrene-divinylbenzene based polymeric resins Sepabeads (R) SP850, Sepabeads (R) SP825L, Amberlite (R) XAD4, Dowex (R) Optipore (R) L-493 and Diaion (R) HP-20. All resins accumulated OA and DTX1 from the P. lima culture with differences in adsorption rate and equilibrium rate. Following statistical evaluation, HP-20, SP850 and SP825L demonstrated... |
Tipo: Text |
Palavras-chave: Polymeric resin; Dinophysistoxin 1; Okadaic acid; SPATT; Prorocentrum lima. |
Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/2008/publication-4739.pdf |
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Sam Lone, Anais. |
Among the applications that facilitate the study of functional processes in living systems, measurement of the spatial distribution of molecules in biological tissues is currently available. Thus, in the field of human health, this application which targets the molecular distributions of altered tissues can be used, for example, in the diagnosis of diseases such as cancers, Alzheimer's disease, muscular myopathy, but also to recognize the distribution of drugs in animal tissues. The principle of imaging by mass spectrometry is to produce a mapping of the surface of a section of tissue, recording at each point a mass spectrum. All these spectra reconstitute so many "ion density maps", called images, that there are peaks of biological interest in the... |
Tipo: Text |
Palavras-chave: Imagerie par spectrométrie de masse; MALDI-TOF; TOF-SIMS; Acide okadaïque; Glande digestive; Mytilus edulis; Imaging by mass spectrometry; MALDI-TOF; TOF-SIMS; Okadaic acid; Digestive Gland; Mytilus edulis. |
Ano: 2016 |
URL: http://archimer.ifremer.fr/doc/00360/47167/47190.pdf |
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GARCÍA,CARLOS; PEREIRA,PAULO; VALLE,LUIS; LAGOS,NÉSTOR. |
Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disease caused by lipid soluble polyether toxins produced by dinoflagellates and accumulated in shellfish. Diarrhetic shellfish poisoning is a worldwide threat to public health and the shellfish industry. To date, only four lipid soluble polyethers have been known as diarrhetic shellfish toxins. Among them, Okadaic acid (OA), Dinophysistoxin 1 (DTX-1, 35-methyl OA), Dinophysistoxin 2 (DTX-2, OA isomers) and Dinophysistoxin 3 (DTX-3, 7-O-acyl-35-methyl OA), all of which have free carboxilic groups. To perform quantitative analysis of DSP toxins in shellfish samples is a requirement, because DSP toxins are endemic in the Chilean mollusks of the southern regions, and although human symptoms of DSP... |
Tipo: Journal article |
Palavras-chave: DSP toxins; Okadaic acid; Dinophysistoxin-1 (DTX-1); Pyrenyldiazomethane (PDAM); Patagonian fjords; Chile. |
Ano: 2003 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602003000200007 |
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